Megaguirus has numerous abilities. At top flight speed she vanishes into a blur, enabling her to surprise an opponent from an unexpected quarter. This high-speed flight also produces high frequency sonic waves capable of shorting out nearby electrical equipment. Her sharp wings can even cut steel and concrete. Her large abdomen ends in a vicious stinger used to pierce into an opponent's hide and drain energy from it. During this process, the opponent is incapable of launching any additional energy-based attacks upon her.
She is one of the major kaiju of Malimors, as she attacked the Kaiju after the Kraken was killed along with Battra, and appeared in the final battle in Tokyo.